Multi-vehicle pileup kills three on Pennsylvania highway 

Harrisburg:  At least three people were killed in a massive crash involving more than 50 vehicles that closed a portion of Pennsylvania's Interstate 81, sending dozens to area hospitals. 

As per officials, the highway was snow-covered when the snow squall came through and caused the pileup, which included up to 60 vehicles. 

The pileup also caused what officials described as a "large fire." 

The crash was first reported between Exit 116 - PA 901 and Exit 119 - Highridge Park Rd. 

Reportedly, three tractor trailers carrying unknown cargo were on fire when emergency personnel arrived and some smaller vehicles were also on fire. 

The National Weather Service had warned of "numerous brief heavy snow squalls with very poor visibility." Before the collision occurred, heavy snow squalls were reported in the area. All lanes were closed. 

Footage uploaded to social media showed a tractor-trailer smash into a large dump truck, turning it nearly 180 degrees. 

Another large truck spewed black smoke and orange flames into the air and an SUV struck a passenger car sending the sedan spinning, narrowly missing its driver who stood on the shoulder of the highway shrouded in snow and fog.